S&P 500 comparison · Health Care

Lilly (Eli) vs Zoetis

Prices at close . Model readings .

Lilly (Eli)

$1,288.30+0.5%
Month: negativeLong run: negative

Zoetis

$77.80−0.55%
Month: positive
Price change

Price change, with the S&P 500 as a benchmark

Percent change in each close since the start of the chosen range, for both companies and the S&P 500 (SPY). Daily closes over the last year, weekly before that and monthly before five years.

In short

How the two compare

On the latest closes (28 Oct 2026), Lilly (Eli) is the larger company by market value ($1.21T against $32.50B). Over the past year Lilly (Eli) returned +56.9% and Zoetis −46.3%, while the S&P 500 returned +12.7%. The latest filed P/E is 51.2 for Lilly (Eli) and 11.3 for Zoetis, and the operating margin 45% against 31%. Over the next 21 sessions the model expects −0.08% for Lilly (Eli), with a 35% chance of a rise, and +0.24% for Zoetis, with a 58% chance. Lilly (Eli)'s long-run fair value is $964.87, a gap of −25.1% to its price; the long-run model view is negative. Zoetis has no published fair value today.

Model view

What the model expects

Expected returns and the chance of a rise from our forecasting models, and the long-run fair value against the price. Readings, not advice.

Model readings:
Expected returnnext 21 sessions
LLY−0.08%
ZTS+0.24%
Chance of a risenext 21 sessions
LLY35%
ZTS58%
Expected returnnext 63 sessions
LLY+0.91%
ZTS+2.55%
Range of outcomes63 sessions, 80% band
LLY−20.3% to +22.1%
ZTS−19% to +24.1%
Chance of a risenext 63 sessionsMembers only · see plans
Long-run fair valueintrinsic value model
LLY$964.8728 Oct 2026
ZTS—The model's fair value falls outside its own interval or at the gap clamp, so it is not a measurement.
Gap to pricefair value against the close
LLY−25.1%
ZTS—The model's fair value falls outside its own interval or at the gap clamp, so it is not a measurement.
Past readings that matchedsign of the 21-session outcome
LLY55%of 269
ZTS42.8%of 269
Price performance

How the prices moved

Price change over each period, with the S&P 500 (SPY) for comparison.

Closes to
1 monthS&P 500: +1.1%
LLY+8.8%
ZTS+10.7%
6 monthsS&P 500: +8.5%
LLY+51.8%
ZTS−31.2%
Year to dateS&P 500: +13.3%
LLY+20.5%
ZTS−37.2%
1 yearS&P 500: +12.7%
LLY+56.9%
ZTS−46.3%
5 yearsS&P 500: +70.7%
LLY+453.1%
ZTS−60.1%
1 year against the S&P 500percentage points
LLY+44.2 pts
ZTS−59.0 pts
Position in the 52-week range0% low, 100% high
LLY94%close $1,288.30 in $804.56 to $1,321.21
ZTS12%close $77.80 in $68.77 to $144.68
Against the 200-day average
LLY+18.6%
ZTS−16.6%
Valuation

What the market pays

Size and the multiples from the latest filed quarter. A P/E on losses reads n/m.

Filings: quarter to
Market value
LLY$1.21T28 Oct 2026
ZTS$32.50B28 Oct 2026
Enterprise valueat the last filing
LLY$1.18T30 Jun 2026
ZTS$37.59B30 Jun 2026
P/Elatest filed
LLY51.2
ZTS11.3
Price to book
LLY33.33
ZTS9.53
EV / EBITDA
LLY35.29
ZTS10.95
Free cash flow yield
LLY1.61%
ZTS7.88%
Dividend yield
LLY0.51%
ZTS2.99%
Questions

Lilly (Eli) or Zoetis: common questions

Which is larger by market value, Lilly (Eli) or Zoetis?

Lilly (Eli), at $1.21T against $32.50B for Zoetis, on the latest closes (28 Oct 2026).

Which has the higher P/E ratio, Lilly (Eli) or Zoetis?

Lilly (Eli) has the higher latest filed P/E, 51.2; Zoetis' is 11.3. Filings: quarter to 30 Jun 2026.

How did Lilly (Eli) and Zoetis move over the past year against the S&P 500?

Over the past year Lilly (Eli) returned +56.9% and Zoetis −46.3%, while the S&P 500 returned +12.7%. Prices at close 28 Oct 2026.

What does the model expect for Lilly (Eli) and Zoetis over the next month?

−0.08% for Lilly (Eli) with a 35% chance of a rise, and +0.24% for Zoetis with a 58% chance, over the next 21 sessions. Model readings 28 Oct 2026. These are model readings, not advice.

How do the operating margins of Lilly (Eli) and Zoetis compare?

The operating margin is 45% for Lilly (Eli) and 31% for Zoetis, and the gross margin 85.8% against 72.7%. Filings: quarter to 30 Jun 2026.

Do Lilly (Eli) and Zoetis shares move together?

Over the past year the correlation of their daily returns was 0.16 (mostly independent); 1 means they always move together, 0 unrelated, −1 opposite. Prices at close 28 Oct 2026.

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The two company pagesLilly (Eli) (LLY) forecast and analysisZoetis (ZTS) forecast and analysis
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BrowseAll Health Care companiesAll comparisonsHow the model readings are made

Model readings are research estimates, not investment advice. Prices: daily closes. Fundamentals: the latest SEC filings. Short interest: FINRA, settlement 30 Sep 2026. A dash means the figure is not in our data; it is never shown as zero. The model view follows a published rule: next month by the sign of the expected return, the long run positive at a fair value 10% or more above the price and negative at 10% or more below it.