S&P 500 comparison · Health Care

AbbVie vs Amgen

Prices at close . Model readings .

AbbVie

$285.99−0.14%
Month: negativeLong run: neutral

Amgen

$451.83+0.87%
Month: negativeLong run: negative
Price change

Price change, with the S&P 500 as a benchmark

Percent change in each close since the start of the chosen range, for both companies and the S&P 500 (SPY). Daily closes over the last year, weekly before that and monthly before five years.

In short

How the two compare

On the latest closes (28 Oct 2026), AbbVie is the larger company by market value ($506.49B against $245.80B). Over the past year AbbVie returned +28.4% and Amgen +59.5%, while the S&P 500 returned +12.7%. The latest filed P/E is 64.6 for AbbVie and 22.8 for Amgen, and the operating margin 37.9% against 35%. Over the next 21 sessions the model expects −0.3% for AbbVie, with a 35% chance of a rise, and −0.19% for Amgen, with a 43% chance. AbbVie's long-run fair value is $263.32, a gap of −7.9% to its price; the long-run model view is neutral. Amgen's long-run fair value is $302.50, a gap of −33.1% to its price; the long-run model view is negative.

Model view

What the model expects

Expected returns and the chance of a rise from our forecasting models, and the long-run fair value against the price. Readings, not advice.

Model readings:
Expected returnnext 21 sessions
ABBV−0.3%
AMGN−0.19%
Chance of a risenext 21 sessions
ABBV35%
AMGN43%
Expected returnnext 63 sessions
ABBV+0.97%
AMGN+1.45%
Range of outcomes63 sessions, 80% band
ABBV−17.2% to +19.2%
AMGN−23.8% to +26.7%
Chance of a risenext 63 sessionsMembers only · see plans
Long-run fair valueintrinsic value model
ABBV$263.3228 Oct 2026
AMGN$302.5028 Oct 2026
Gap to pricefair value against the close
ABBV−7.9%
AMGN−33.1%
Past readings that matchedsign of the 21-session outcome
ABBV58.4%of 269
AMGN55.8%of 269
Price performance

How the prices moved

Price change over each period, with the S&P 500 (SPY) for comparison.

Closes to
1 monthS&P 500: +1.1%
ABBV+8.6%
AMGN+6.7%
6 monthsS&P 500: +8.5%
ABBV+41.3%
AMGN+35.5%
Year to dateS&P 500: +13.3%
ABBV+28.1%
AMGN+40.9%
1 yearS&P 500: +12.7%
ABBV+28.4%
AMGN+59.5%
5 yearsS&P 500: +70.7%
ABBV+213.1%
AMGN+151.8%
1 year against the S&P 500percentage points
ABBV+15.7 pts
AMGN+46.8 pts
Position in the 52-week range0% low, 100% high
ABBV95%close $285.99 in $189.40 to $291.40
AMGN98%close $451.83 in $280.23 to $454.66
Against the 200-day average
ABBV+21.8%
AMGN+22%
Valuation

What the market pays

Size and the multiples from the latest filed quarter. A P/E on losses reads n/m.

Filings: quarter to
Market value
ABBV$506.49B28 Oct 2026
AMGN$245.80B28 Oct 2026
Enterprise valueat the last filing
ABBV$501.57B30 Jun 2026
AMGN$234.86B30 Jun 2026
P/Elatest filed
ABBV64.6
AMGN22.8
Price to book
ABBV-75.69
AMGN16.85
EV / EBITDA
ABBV28.85
AMGN16.08
Free cash flow yield
ABBV4.09%
AMGN5.17%
Dividend yield
ABBV2.69%
AMGN2.68%
Questions

AbbVie or Amgen: common questions

Which is larger by market value, AbbVie or Amgen?

AbbVie, at $506.49B against $245.80B for Amgen, on the latest closes (28 Oct 2026).

Which has the higher P/E ratio, AbbVie or Amgen?

AbbVie has the higher latest filed P/E, 64.6; Amgen's is 22.8. Filings: quarter to 30 Jun 2026.

How did AbbVie and Amgen move over the past year against the S&P 500?

Over the past year AbbVie returned +28.4% and Amgen +59.5%, while the S&P 500 returned +12.7%. Prices at close 28 Oct 2026.

What does the model expect for AbbVie and Amgen over the next month?

−0.3% for AbbVie with a 35% chance of a rise, and −0.19% for Amgen with a 43% chance, over the next 21 sessions. Model readings 28 Oct 2026. These are model readings, not advice.

How do the operating margins of AbbVie and Amgen compare?

The operating margin is 37.9% for AbbVie and 35% for Amgen, and the gross margin 74.7% against 72%. Filings: quarter to 30 Jun 2026.

Do AbbVie and Amgen shares move together?

Over the past year the correlation of their daily returns was 0.47 (loosely together); 1 means they always move together, 0 unrelated, −1 opposite. Prices at close 28 Oct 2026.

In the consoleCompare up to four companies with every model readingMembers see the 63-session chance of a rise and all four horizons, side by side in Research › Compare.
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The two company pagesAbbVie (ABBV) forecast and analysisAmgen (AMGN) forecast and analysis
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BrowseAll Health Care companiesAll comparisonsHow the model readings are made

Model readings are research estimates, not investment advice. Prices: daily closes. Fundamentals: the latest SEC filings. Short interest: FINRA, settlement 30 Sep 2026. A dash means the figure is not in our data; it is never shown as zero. The model view follows a published rule: next month by the sign of the expected return, the long run positive at a fair value 10% or more above the price and negative at 10% or more below it.